DYNAMIC insights into MRD responses early after resection of NSCLC

This protocol describes the feasibility to perform miRNA profiling in exosomes, released in plasma of NSCLC patients, through a commercial exosome isolation kit with Proteinase K and RNAse treatments, in order to avoid circulating miRNAs contamination and evaluate their biomarker features in...

Source: Alomari, S., et al. Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection. J. Vis. Exp. (2022)This video demonstrates the use of a minimally invasive resection system (MIRS) to excise tumor tissue from an anesthetized mouse implanted with a tumor. The procedure involves securing the mouse onto a stereotactic frame, reopening the previous surgical site to access the brain, and inserting a specialized cannula that utilizes suction and a...

Gathering customer insights is a multifaceted process aimed at comprehending the intricacies of customer behavior and preferences. It employs various methods such as customer surveys, feedback analysis, monitoring social media, and tracking interactions across different touchpoints. Through these channels, businesses accumulate valuable data that provides a comprehensive view of customer experiences and expectations.
Analyzing these insights equips businesses with the knowledge to tailor their...

Hypothalamic hamartomas are rare, non-neoplastic congenital malformations mainly arising from the inferior hypothalamus or tuber cinereum. Surgical treatment is one of the most effective options, and the surgical approach must be precisely determined for each patient. Here, we describe the full-endoscopic technique for resecting hypothalamic...

This protocol details a minimally invasive endoscopic technique for the removal of third ventricular colloid cysts. It provides a comprehensive overview of preoperative preparations, surgical steps, and postoperative outcomes, emphasizing reduced recovery time, minimal complications, and total cyst removal. This approach is a safe and effective alternative to traditional...

A reversible chemical reaction represents a chemical process that proceeds in both forward (left to right) and reverse (right to left) directions. When the rates of the forward and reverse reactions are equal, the concentrations of the reactant and product species remain constant over time and the system is at equilibrium. A special double arrow is used to emphasize the reversible nature of the reaction. The relative concentrations of reactants and products in equilibrium systems vary greatly;...