Carbimazole-induced Anaphylactic Shock: A Case Report

Area of Science:

• Endocrinology
• Pharmacology
• Allergy and Immunology

Background:

• Carbimazole is a commonly prescribed antithyroid medication.
• Anaphylactic shock is a rare but life-threatening adverse drug reaction.

Purpose of the Study:

• To report a rare case of anaphylactic shock induced by carbimazole.
• To highlight the importance of patient counseling regarding rare side effects of carbimazole.

Main Methods:

• Case report of a 40-year-old female patient treated for thyrotoxicosis.
• Observation of anaphylactic shock symptoms after a single dose of carbimazole.

Main Results:

• The patient presented with sweating, shortness of breath, and altered sensorium after carbimazole administration.
• The patient was successfully treated for anaphylactic shock.

Conclusions:

• Carbimazole can induce anaphylactic shock without preceding allergic manifestations.
• Awareness and prompt medical attention are crucial for managing rare adverse drug reactions like carbimazole-induced anaphylaxis.