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Related Experiment Video

Updated: Jan 20, 2026

A Procedure for Implanting Organized Arrays of Microwires for Single-unit Recordings in Awake, Behaving Animals
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Anesthetic Errors During Procedures in the United States.

Punit Singh1, Mostafa Maita1, John Lacci1

  • 1From the Departments of Anesthesiology and Neurosurgery and the School of Medicine, University of Texas Health San Antonio, San Antonio.

Southern Medical Journal
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Anesthetic errors, though infrequent, occurred in US hospitals between 2007-2014. Patients with fluid disorders and coagulopathies faced higher mortality risks from these errors.

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Area of Science:

  • Anesthesiology
  • Patient Safety
  • Healthcare Quality

Background:

  • Anesthetic errors, including overdose and incorrect medication administration, pose risks to patient safety.
  • Understanding the incidence and outcomes of these errors is crucial for improving healthcare quality.

Purpose of the Study:

  • To determine the incidence of anesthetic errors and associated mortality per hospital discharges in the United States.
  • To investigate the relationship between patient comorbidities and mortality following anesthetic errors.

Main Methods:

  • Retrospective analysis of the Nationwide Inpatient Sample (NIS) database from 2007-2014.
  • Inclusion of inpatient discharges with complications from incorrect anesthetic administration (overdose or wrong medication).

Main Results:

  • A total of 17,116 anesthetic errors were reported, showing a 44% decrease from 2007 to 2014.
  • The overall mortality rate from anesthetic errors was 0.77% (131 deaths), with a decreasing trend observed over the study period.
  • Fluid and electrolyte disorders (OR 8.82) and coagulopathies (OR 5.26) were significantly associated with increased mortality.

Conclusions:

  • Anesthetic errors, while infrequent, remain a concern in US hospitals.
  • Specific comorbidities, particularly fluid/electrolyte disorders and coagulopathies, significantly increase patient mortality risk.
  • Targeted interventions for high-risk patient groups may enhance safety and reduce anesthetic-related deaths.