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Updated: Jan 20, 2026

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Published on: March 4, 2022
[Unilateral pigmentary retinopathy : about 2 cases]
J F Chapelle1, A C Chapelle1, A Georges1
1Service d'Ophtalmologie, CHU Liège, Belgique.
Two patients presented with unilateral pigmentary retinopathy, potentially linked to Bartonella or multiple sclerosis. Long-term follow-up is crucial to exclude asymmetrical bilateral retinitis pigmentosa.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Neuro-ophthalmology
Background:
- Retinitis pigmentosa (RP) is a group of inherited retinal diseases.
- Unilateral presentations are rare, raising diagnostic challenges.
- Pigmentary changes on fundus examination are characteristic of RP.
Observation:
- Two cases of unilateral retinal involvement with pigmentary lesions were observed.
- Fundus examination revealed morphological and functional retinal aspects suggestive of RP.
- One patient had a history of Bartonella infection; the other had pre-existing multiple sclerosis.
Findings:
- A diagnosis of unilateral pigmentary retinopathy was made in both cases.
- The unilateral presentation was associated with Bartonella in one case and multiple sclerosis in the other.
- These associations suggest potential triggers or related conditions for the retinopathy.
Implications:
- Unilateral pigmentary retinopathy can be associated with infectious or neurological conditions.
- Careful patient history and investigation are essential for accurate diagnosis.
- Extended follow-up is necessary to monitor for potential progression or involvement of the other eye, suggesting asymmetrical bilateral retinitis pigmentosa.
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