[Kingella kingae bone and joint infections]

Area of Science:

• Pediatric infectious diseases
• Microbiology
• Orthopedic infections

Background:

• Kingella kingae is increasingly recognized as a significant cause of pediatric bone and joint infections (BJI).
• Diagnosis of Kingella kingae infections has been historically challenging.
• The advent of Polymerase Chain Reaction (PCR) has improved pathogen detection.

Observation:

• This report details six cases of probable or confirmed Kingella kingae BJI in children.
• The affected children were aged between 6 and 48 months.
• Clinical presentations varied, highlighting the need for broad diagnostic considerations.

Findings:

• Polymerase Chain Reaction (PCR) is crucial for identifying Kingella kingae in bone and joint infections.
• Kingella kingae is an important pathogen in children aged 6 to 48 months presenting with BJI.
• Prompt and accurate diagnosis is key to effective management.

Implications:

• Increased awareness and utilization of molecular diagnostic methods are essential for pediatric BJI.
• Effective antibiotic therapy, guided by timely diagnosis, ensures a favorable prognosis.
• Understanding the epidemiology of Kingella kingae aids in preventing and managing pediatric infections.