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An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Palpebral Tarsal Solitary Neurofibroma
Bülent Yazıcı1, Sertaç Argun Kıvanç1, Uğur Yayla1
1Uludag University Faculty of Medicine, Department of Ophthalmology, Bursa, Turkey
A rare eyelid tumor, solitary neurofibroma, was successfully removed from a patient without neurofibromatosis. This benign peripheral nerve sheath tumor did not recur after surgical excision.
Area of Science:
- Ophthalmology
- Dermatology
- Oncology
Background:
- Solitary neurofibroma is a rare, benign peripheral nerve sheath tumor.
- It is often associated with neurofibromatosis type 1.
- Eyelid neurofibromas are uncommon.
Observation:
- A 68-year-old man presented with a 6-month history of a right upper eyelid subcutaneous mass.
- The mass was a 12x8 mm round, reddish lesion on the tarsal plate.
- Histological examination confirmed solitary neurofibroma.
Findings:
- The palpebral tarsal solitary neurofibroma was surgically excised.
- The patient experienced no recurrence during a 34-month follow-up period.
- This case represents the seventh reported instance of solitary neurofibroma of the eyelid.
Implications:
- Surgical excision is an effective treatment for solitary neurofibroma of the eyelid.
- Solitary neurofibromas can occur in patients without neurofibromatosis.
- Further case reports are valuable for understanding this rare condition.
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