Anxiety and depression relationship with coronary slow flow

Area of Science:

• Cardiology
• Psychiatry
• Medical Research

Background:

• Psychiatric disorders like depression and anxiety are known to be associated with coronary artery disease (CAD).
• Coronary slow flow (CSF) is a common manifestation of CAD, but its specific relationship with psychiatric conditions is not well-established.
• This study aims to investigate the link between psychiatric disorders and CSF.

Purpose of the Study:

• To determine the association between psychiatric disorders (depression and anxiety) and coronary slow flow (CSF).
• To identify predictors of CSF in patients undergoing elective coronary angiography.
• To explore the correlation between the severity of CSF and the severity of psychological symptoms.

Main Methods:

• A cross-sectional observational study involving 50 patients with CSF and 50 with normal coronaries, diagnosed via coronary angiography (CAG).
• Beck Anxiety Inventory and Beck Depression Inventory were used for psychiatric assessment.
• Lipid profiles were analyzed, and CSF was quantified using the "Thrombolysis In Myocardial Infarction" frame count.

Main Results:

• Patients with CSF exhibited higher rates of male gender, smoking, high total cholesterol, low-density lipoproteins, and triglycerides compared to the control group.
• Depression and anxiety scores were significantly elevated in the CSF group.
• Multivariate analysis identified male gender, depression, and high triglycerides as independent predictors of CSF. A strong correlation was found between CSF severity and both anxiety and depression scores.

Conclusions:

• Psychiatric depression, male gender, and high triglycerides are strongly associated with CSF in patients undergoing elective CAG.
• The severity of CSF correlates significantly with the severity of both anxiety and depression.
• Further research is recommended to evaluate the impact of psychological interventions on CSF and patient outcomes.