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Published on: May 6, 2020
Retrograde Tibioperoneal Access for Complex Infrainguinal Occlusions: Short- and Long-Term Outcomes of 554
Andrej Schmidt1, Yvonne Bausback1, Michael Piorkowski2
1Division of Angiology, Department of Internal Medicine, Neurology and Dermatology, University Hospital Leipzig, Leipzig, Germany.
Insights
Retrograde tibioperoneal access offers a safe and effective endovascular treatment for chronic total occlusions (CTOs) when antegrade approaches fail. This method demonstrates a high success rate with rare complications, improving outcomes for patients with critical limb ischemia.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Therapy
Background:
- Antegrade recanalization of peripheral chronic total occlusions (CTOs) often has a high failure rate.
- Retrograde tibioperoneal artery access is an alternative strategy to overcome limitations of the antegrade approach.
Purpose of the Study:
- To evaluate the short- and long-term efficacy and safety of retrograde tibioperoneal access for endovascular treatment of infrainguinal CTOs.
- To report outcomes in patients with critical limb ischemia (CLI) and claudicants.
Main Methods:
- Retrospective single-center cohort study of 554 infrainguinal occlusions requiring retrograde tibioperoneal access.
- Data collection included access techniques, lesion crossing, treatment modalities, and short- and long-term outcomes up to 4 years.
- Survival analysis was used for long-term outcome assessment.
Main Results:
- Retrograde access was successful in 98.6%, with lesion crossing achieved in 95.1%.
- Complications at the distal puncture site were infrequent (3.3%).
- One-year freedom from target lesion revascularization was 74.6% for claudicants and 62.2% for CLI patients; restenosis rates were 67.5% and 36.0%, respectively.
Conclusions:
- Retrograde tibioperoneal access is a safe and effective option for complex CTO recanalization following failed antegrade attempts.
- Puncture site complications are rare, supporting the safety profile of this technique.
Objectives:
This study sought to report short- and long-term efficacy and safety outcomes of retrograde tibioperoneal access for endovascular treatment of chronic total occlusions (CTOs).
Background:
Antegrade recanalization of peripheral CTO is associated with a high failure rate and retrograde puncture of tibioperoneal arteries has been adopted to overcome this limitation.
Methods:
Within a retrospective single center cohort study, data of 554 infrainguinal occlusions were acquired in which a retrograde puncture of at least 1 infrapopliteal artery became necessary. Techniques used for access, retrograde lesion crossing, and antegrade treatment modalities were recorded. Next to short-term outcomes, long-term results through 4 years were described using survival analysis.
Results:
The majority of patients (71.5%) had critical limb ischemia (CLI) and occlusion locations were the femoropopliteal segment (35.9%), infrapopliteal segment (42.6%), or both segments (21.5%). Retrograde access was most commonly performed via the proximal (28%) or distal (34%) anterior tibial artery. Retrograde access could be established in 98.6% and subsequent lesion crossing was successful in 95.1%. Complications due to distal puncture were rare (3.3%). At 1 year, freedom from target lesion revascularization and restenosis were 74.6 ± 3.7% and 67.5 ± 4.4% in claudicants and 62.2 ± 2.8% and 36.0 ± 4.4% in CLI patients, respectively. Late complications at the distal puncture site after a median follow-up time of 234 days comprised 1 stenosis, 7 occlusions, and 3 clinically nonrelevant arteriovenous fistula occurring only in CLI patients.
Conclusions:
Retrograde tibioperoneal access is a safe option for recanalization of complex CTOs after a failed antegrade approach. Complications at the puncture site were rare.
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