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Related Experiment Videos

[Gold-induced systemic lupus erythematosus].

D Körholz1, W Nürnberger, U Göbel

  • 1Zentrum für Kinderheilkunde, Universität Düsseldorf.

Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
|September 1, 1988
PubMed
Summary

Gold therapy for severe polyarthritis in a child led to pericarditis and autoantibodies. Symptoms resolved after stopping gold, with autoantibodies normalizing within a year, indicating a potential drug-induced reaction.

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Area of Science:

  • Rheumatology
  • Pediatric Rheumatology
  • Immunology

Background:

  • Severe exudative polyarthritis is a debilitating condition often requiring disease-modifying antirheumatic drugs.
  • Gold salts, such as sodium aurothiomalate, have been used historically for treating inflammatory arthritis.
  • Drug-induced autoimmunity is a recognized phenomenon associated with various medications.