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Updated: Jan 20, 2026

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
Published on: February 28, 2015
Selective switching of multiple azobenzenes
Andreas H Heindl1,2, Jonathan Becker3, Hermann A Wegner1,2
1Institute of Organic Chemistry , Justus Liebig University , Heinrich-Buff-Ring 17 , 35392 Giessen , Germany .
Abstract:
Multi-state photoswitchable compounds are highly attractive for application in data storage or multi-responsive materials. In this work, a trisazobenzene macrocycle capable of three-state isomerization is presented. The compound can be switched into each of the states with more than 70% of the isomer solely by light and heat as stimuli representing the first example for an oligo-azobenzene containing identical photochromic units which can be selectively adressed. Detailed spectroscopic, crystallographic, HPLC as well as computational investigations and the comparison to a less and a higher strained derivative revealed macrocyclic ring strain to be responsible for the compounds unique isomerization behavior.
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