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Updated: Jan 20, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Benefit-risk evaluation: the past, present and future
1Sanofi, Bridgewater, 55 Corporate Drive, Bridgewater, NJ 08807, USA.
Abstract:
In the last two decades there has been a shift in the approach to evaluating the benefit-risk (BR) profiles of medicinal products from an unstructured, subjective, and inconsistent, to a more structured and objective, process. This article describes that shift from a historical perspective; the past, the present, and the future, and highlights key events that played critical roles in changing the field.
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