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Updated: Jan 20, 2026

Experimental Metastatic Melanoma Mouse Model: A Platform to Study the Metastatic Potential of Melanoma Cells in the Lungs
Published on: April 30, 2023
Metastatic melanoma to the testis
Madhavi Patnana1, Brinda Rao Korivi1, Catherine E Devine1
1Department of Diagnostic Radiology, Anatomical, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Metastatic melanoma to the testis is rare. This case report details ultrasound and PET-CT imaging findings for this uncommon presentation, highlighting the role of diagnostic imaging.
Area of Science:
- Oncology
- Radiology
- Uropathology
Background:
- Metastatic melanoma to the testis is an exceedingly rare clinical entity.
- Testicular metastases typically originate from primary tumors in the prostate, lung, kidney, or gastrointestinal tract.
- Melanoma is an uncommon source of secondary testicular tumors.
Purpose of the Study:
- To present the diagnostic imaging findings of metastatic melanoma to the testis.
- To review the literature on this rare condition.
- To discuss the utility of ultrasound and positron emission tomography-computed tomography (PET-CT) in diagnosing testicular metastases from melanoma.
Main Methods:
- Case report of a patient with metastatic melanoma to the testis.
- Review of relevant medical literature.
- Analysis of ultrasound and PET-CT imaging characteristics.
Main Results:
- Ultrasound demonstrated focal hypoechoic lesions within the testis.
- Positron emission tomography-computed tomography (PET-CT) revealed increased fluorodeoxyglucose (FDG) uptake in the affected testis, consistent with metastatic disease.
- Imaging findings were correlated with histopathological diagnosis.
Conclusions:
- Ultrasound and PET-CT are valuable tools for diagnosing metastatic melanoma to the testis.
- Early and accurate diagnosis through advanced imaging can aid in patient management.
- Increased awareness of this rare presentation is crucial for clinicians and radiologists.
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