Related Experiment Video
Updated: Jan 20, 2026

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
Published on: March 14, 2018
Trabecular bone score (TBS) as a noninvasive and complementary tool for clinical diagnosis of bone structure in
Jowita Halupczok-Żyła1, Łukasz Gojny1, Marek Bolanowski2
1Department and Clinic of Endocrinology, Diabetes, and Isotope Therapy, Wrocław Medical University, Poland.
Abstract:
Trabecular bone score (TBS) index has recently been obtained as a result of textural greyscale analysis of DXA images. Because it enables the assessment of bone microarchitectural texture, TBS may be useful in evaluating bone quality. This study explores the current knowledge of the use of TBS in patients with endocrine disorders with co-occurring bone structure changes. Currently, the clinical importance TBS was verified in terms of disorders of the growth hormone/insulin-like growth factor 1 (GH/IGF-I) axis, glucocorticoid excess, thyroid and parathyroid disease, as well as in diabetes mellitus type 1 and 2. It has been clarified that patients suffering from various endocrinopathies are a group in which TBS should be used routinely because it correlates with clinical factors and may improve patient management in various endocrine disorders.
Related Concept Videos
09:36Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
06:59Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
08:49Models of Bone Metastasis
Bone Structure
09:09Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection

