Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells12:43

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells

12.2K
Evaluated in syngeneic immunocompetent hosts, cancer stem cell (CSC) based dendritic cell (DC) vaccine demonstrated significantly higher antitumor immunity than traditional DC vaccines pulsed with heterogeneous bulk tumor...
12.2K
Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing05:17

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

353
This protocol describes an automated, ISO15189-accredited next-generation sequencing workflow for detecting targetable genomic alterations in non-small cell lung cancer (NSCLC) formalin-fixed paraffin-embedded...
353
Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies07:29

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies

20.1K
Pancreatic cancer stem cells (CSCs) can be expanded in vitro using the anchorage-independent sphere culture technique, which represents a powerful tool to study CSC biology and can serve as the first step to develop novel CSC-targeting therapies. Here the methodology for expanding, analyzing and targeting of pancreatic CSCs is...
20.1K
Radiosensitivity of Cancer Stem Cells in Lung Cancer Cell Lines09:45

Radiosensitivity of Cancer Stem Cells in Lung Cancer Cell Lines

7.5K
The presence of cancer stem cells have been associated with relapse or poor outcomes after radiotherapy. This manuscript describes the methods to study the radiosensitivity of cancer stem cells in lung cancer cell...
7.5K
Isolation of Cancer Stem Cells From Human Prostate Cancer Samples07:16

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples

14.6K
The isolation of cancer stem cells (CSCs) directly from human tissues is requisite for their biological characterization. This manuscript describes a methodology for the isolation of prostate CSCs from human tissues, while also providing tips on troubleshooting difficult...
14.6K
Isolation and Functional Assessment of Human Breast Cancer Stem Cells from Cell and Tissue Samples07:03

Isolation and Functional Assessment of Human Breast Cancer Stem Cells from Cell and Tissue Samples

5.0K
This experimental protocol describes the isolation of BCSCs from breast cancer cell and tissue samples as well as the in vitro and in vivo assays that can be used to assess BCSC phenotype and...
5.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Actively targeted dendrimer-metal organic framework drug delivery nanoplatform for the treatment of neuroblastoma.

RSC advances·2026
Same author

Influence of micro and nano particles on the mechanical, morphological and thermal properties of HDPE/PP blends.

Scientific reports·2026
Same author

Integrative Systems-Level Transcriptomic Network Analysis Identifies Candidate Genes Associated with Biofilm Formation and Virulence in <i>Pseudomonas aeruginosa</i>.

International journal of molecular sciences·2026
Same author

Design and optimization of a Cu-MOF@graphene oxide nanozyme for point-of-care colorimetric determination of sarcosine and H<sub>2</sub>O<sub>2</sub>.

RSC advances·2026
Same author

Fortified Long-acting Ocular Gel Laden with Nanoformulated Dexamethasone for Dry Eye Therapy.

AAPS PharmSciTech·2026
Same author

Folate-functionalized core-shell nanocarrier System for sustained and targeted delivery of <i>Saraca Indica</i> for breast cancer treatment.

Drug development and industrial pharmacy·2026

Related Experiment Video

Updated: Jan 20, 2026

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells
12:43

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells

Published on: January 6, 2014

12.2K

Next-generation nanotheranostics targeting cancer stem cells.

Asmaa Reda1,2, Salma Hosseiny1, Ibrahim M El-Sherbiny1

  • 1Nanomedicine Division, Center for Materials Science, Zewail City of Science & Technology, 12578, Giza, Egypt.

Nanomedicine (London, England)
|September 7, 2019
PubMed
Summary

Cancer stem cells (CSCs) drive aggressive cancers and resist conventional treatments. Nanotechnology offers promising nanotheranostics for targeted cancer therapy and early detection by addressing CSCs.

Keywords:
cancercancer stem cellsnanotheranosticssmart nanoparticlessustained releasetargeting

More Related Videos

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
05:17

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

Published on: October 10, 2025

353
Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies
07:29

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies

Published on: June 20, 2015

20.1K

Related Experiment Videos

Last Updated: Jan 20, 2026

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells
12:43

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells

Published on: January 6, 2014

12.2K
Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
05:17

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

Published on: October 10, 2025

353
Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies
07:29

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies

Published on: June 20, 2015

20.1K

Area of Science:

  • Oncology
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Cancer is a leading cause of death, driven by immortal cancer stem cells (CSCs).
  • CSCs possess self-renewal and proliferation capabilities, contributing to treatment resistance.
  • Conventional therapies often fail to eliminate CSCs, highlighting a need for novel strategies.

Purpose of the Study:

  • To explore the potential of nanotechnology in developing advanced cancer treatments.
  • To introduce nanotheranostics as a solution for targeting cancer stem cells.
  • To discuss the integration of diagnostic and therapeutic agents in nanomedicine for cancer.

Main Methods:

  • Review of current advancements in nanotechnology for cancer therapy.
  • Focus on the development of multifunctional nanoparticles for cancer stem cell targeting.
  • Integration of diagnostic, therapeutic, and targeting functionalities within nanocarriers.

Main Results:

  • Nanotheranostics offer a multifunctional 'all-in-one' approach to cancer treatment.
  • These nanoparticles can be designed for biocompatibility and biodegradability.
  • Potential for improved early detection, diagnosis, and treatment of cancer.

Conclusions:

  • Nanotheranostics represent a significant advancement in combating cancer, particularly CSCs.
  • The integration of multiple functions in nanoparticles enhances therapeutic efficacy.
  • Targeting cancer stem cells with nanotheranostics opens new avenues for effective cancer management.