Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

A Rat Dry Eye Model with Lacrimal Gland Dysfunction Induced by Scopolamine04:06

A Rat Dry Eye Model with Lacrimal Gland Dysfunction Induced by Scopolamine

2.8K
Here, we establish a rat model of lacrimal gland dysfunction to provide a basis for the study of aqueous-deficient dry...
2.8K
Establishment of A Mouse Model of Aqueous Deficiency Dry Eye05:21

Establishment of A Mouse Model of Aqueous Deficiency Dry Eye

1.3K
Here, we present a method to establish a mouse model of aqueous-deficient dry eye by excising the extraorbital and infraorbital lacrimal glands and evaluate the changes in the ocular surface in aqueous deficiency dry...
1.3K
In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation08:13

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

487
This article demonstrates the operation and effect of in vivo confocal microscopy in the diagnosis and treatment of dry eye and investigates the application and outcomes of in vivo confocal microscopy to provide a basis for future...
487
Press Needle: A Traditional Chinese Medicine Therapy for Myopia Patients with Dry Eye05:26

Press Needle: A Traditional Chinese Medicine Therapy for Myopia Patients with Dry Eye

2.5K
Here, we present a protocol to standardize the operation of acupuncture in the treatment of myopia with dry eye.
2.5K
Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits07:43

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

10.9K
A novel approach is presented to induce chronic dry eye disease in rabbits by surgically removing all orbital lacrimal glands. This method, distinct from those previously reported, produces a stable, reproducible model of aqueous deficient dry eye well suited to study tear physiology and pathophysiology and ocular...
10.9K
Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-1906:29

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

2.7K
The present protocol describes the cross-sectional research performed on 40 healthy subjects between the ages of 20 and 45 to assess the prevalence of dry eye syndrome (DES) during COVID-19. The OSDI survey evaluated DES, and the advanced ophthalmic systems (AOS) software was used to assess limbal...
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Benchmarking and fine-tuning vision-language models on a visual question answering dataset for myopic maculopathy.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2026
Same author

Individualized Estimation of Baseline Retinal Nerve Fiber Layer Thickness Using Conditional Variational Autoencoder.

Ophthalmology science·2025
Same author

Corrigendum to "Controversies, consensuses and guidelines on Small Incision Lenticule Extraction (SMILE) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS)" [Asia-Pac J Ophthalmol (2025) 100221].

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2025
Same author

Controversies, consensuses and guidelines on Small Incision Lenticule Extraction (SMILE) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS).

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2025
Same author

Controversies, consensuses and guidelines on posterior chamber phakic intraocular lens for the correction of myopia and myopic astigmatism in healthy phakic eyes by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO) and the Asia-Pacific Myopia Society (APMS).

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2025
Same author

Optimizing Diagnosis and Management of Dry Eye Disease: A Practical Framework for Hong Kong.

Ophthalmology and therapy·2025

Related Experiment Video

Updated: Jan 20, 2026

Author Spotlight: Challenges in Developing Dry Eye Animal Models and Future Research Directions
04:06

Author Spotlight: Challenges in Developing Dry Eye Animal Models and Future Research Directions

Published on: February 9, 2024

2.8K

Dry Eyes After SMILE.

Angela H Y Wong1, Rachel K Y Cheung2, Wee Nie Kua1

  • 1Department of Ophthalmology, Tuen Mun Hospital, Hong Kong, China.

Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
|September 7, 2019
PubMed
Summary
This summary is machine-generated.

Small Incision Lenticule Extraction (SMILE) may cause fewer dry eye complications than femtosecond-laser-assisted in situ keratomileusis (FS-LASIK) after laser vision correction, potentially leading to earlier recovery and better corneal sensitivity.

More Related Videos

Establishment of A Mouse Model of Aqueous Deficiency Dry Eye
05:21

Establishment of A Mouse Model of Aqueous Deficiency Dry Eye

Published on: November 1, 2024

1.3K
In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation
08:13

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

Published on: November 11, 2025

487

Related Experiment Videos

Last Updated: Jan 20, 2026

Author Spotlight: Challenges in Developing Dry Eye Animal Models and Future Research Directions
04:06

Author Spotlight: Challenges in Developing Dry Eye Animal Models and Future Research Directions

Published on: February 9, 2024

2.8K
Establishment of A Mouse Model of Aqueous Deficiency Dry Eye
05:21

Establishment of A Mouse Model of Aqueous Deficiency Dry Eye

Published on: November 1, 2024

1.3K
In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation
08:13

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

Published on: November 11, 2025

487

Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Ocular Surface Disease

Background:

  • Dry eye is a common complication following laser vision correction.
  • Small Incision Lenticule Extraction (SMILE) is a flapless procedure with a smaller incision, theoretically reducing dry eye incidence.
  • Both SMILE and femtosecond-laser-assisted in situ keratomileusis (FS-LASIK) cause temporary dry eye issues.

Purpose of the Study:

  • To review and compare the impact of SMILE versus FS-LASIK on dry eye parameters.
  • To analyze short-term and long-term effects on dry eye signs, symptoms, and corneal sensitivity.
  • To discuss study limitations and discrepancies in current research.

Main Methods:

  • Literature review comparing SMILE and FS-LASIK for dry eye complications.
  • Analysis of studies examining ocular surface parameters and corneal sensitivity.
  • Discussion of mechanisms of dry eye post-laser vision correction.

Main Results:

  • Both SMILE and FS-LASIK induce transient dry eye worsening.
  • SMILE shows promise for fewer negative impacts on ocular surface parameters and earlier recovery.
  • SMILE may result in less corneal denervation and improved corneal sensitivity compared to FS-LASIK.

Conclusions:

  • SMILE appears to have a potentially better dry eye profile compared to FS-LASIK.
  • Further high-quality, randomized controlled trials with standardized protocols are needed.
  • Standardized postoperative care is crucial for accurately evaluating dry eye after SMILE.