Related Experiment Video
Updated: Jan 20, 2026
02:48
Developing Myopia in a Mouse Model Through Lens-Induced Defocusing
Published on: April 28, 2025
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Future Developments in SMILE: Higher Degree of Myopia and Hyperopia
1Tianjin Eye Hospital, Nankai University Affiliated Eye Hospital, Clinical College of Ophthalmology, Tianjin Medical University, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin, China.
Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
|September 7, 2019
Summary
Small Incision Lenticule Extraction (SMILE) shows promise for high myopia and hyperopia correction. However, it is not suitable for extremely high myopia or compound hyperopic astigmatism, requiring further improvements.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Laser Vision Correction
Background:
- Small Incision Lenticule Extraction (SMILE) is an advanced one-step laser vision correction procedure.
- It utilizes a femtosecond laser to treat myopia and myopic astigmatism, demonstrating good clinical outcomes.
- Despite its success, concerns remain regarding its application in specific refractive errors.
Purpose of the Study:
- To review published clinical outcomes of SMILE for high myopia correction.
- To explore the feasibility and effectiveness of SMILE in hyperopia correction.
- To identify limitations and areas for improvement in SMILE technology.
Main Methods:
- Systematic review of existing clinical studies on SMILE.
- Analysis of data concerning efficacy, safety, predictability, and stability.
- Evaluation of SMILE's performance across different refractive error ranges.
Main Results:
- SMILE demonstrates acceptable outcomes for high myopia correction (less than 10.0 diopters).
- The procedure is feasible and effective for treating hyperopia.
- Undercorrection and regression were observed in extremely high myopia cases, similar to LASIK.
- Compound hyperopic astigmatism cannot currently be corrected with SMILE.
Conclusions:
- SMILE is a viable option for moderate high myopia and hyperopia.
- Further technical and clinical advancements are necessary for SMILE to address a broader range of refractive errors and become more competitive.
- Limitations in treating extremely high myopia and compound hyperopic astigmatism necessitate ongoing research and development.
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