Related Experiment Video
Updated: Jan 19, 2026
A Flow Cytometry-Based Cytotoxicity Assay for the Assessment of Human NK Cell Activity
Published on: August 9, 2017
Chemical constituents from Ginkgo biloba leaves and their cytotoxicity activity
Penghua Shu1, Mengyuan Sun2, Junping Li2
1School of Chemistry and Chemical Engineering, Xuchang University, 88 Bayi Road, Xuchang, 461000, Henan, People's Republic of China. shupenghua@yeah.net.
Abstract:
One novel neoligan glucoside, Ginkgoside B (1), and one new glucose ester, 6-O-(4-hydroxyhydrocinnamoyl)-D-glucopyranose (2), along with nine known compounds (3-11) were isolated from the ethanol extract of Ginkgo biloba leaves. Their structures were elucidated by combination of spectroscopic analyses and alkaline methanolysis. The absolute configuration of compound 1 was determined by single-crystal X-ray diffraction. All the isolated compounds were evaluated for their cytotoxicity activities, and compound 11 exhibited IC50 values of 36.20 and 58.95 μM against 5637 and HeLa cell lines, respectively.
Related Concept Videos
02:14Leaving Groups
In general, in a nucleophilic substitution reaction, a nucleophile displaces a functional group, called the leaving group, from the substrate to give a substituted product. A leaving group departs the substrate molecule through heterolytic cleavage, taking the pair of electrons with it to become a relatively stable weak base in the form of an anion or a neutral molecule.
In a...
03:10An Assay to Measure Chemically-Induced Cytotoxicity in Human Precision-Cut Lung Slices
01:10Thermodynamics: Chemical Potential and Activity
The thermodynamic equilibrium constant is more accurately defined in terms of activity rather than concentration.
06:08A Flow Cytometry-Based Cytotoxicity Assay for the Assessment of Human NK Cell Activity
11:25Cell Specific Analysis of Arabidopsis Leaves Using Fluorescence Activated Cell Sorting
07:16High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC