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Updated: Jan 19, 2026

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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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The sex ratio at birth (1)
1Academic Department of Paediatrics, Medical School, Mater Dei Hospital, Malta.
Early Human Development
|September 9, 2019
Summary
This series explores theories influencing the sex ratio at birth (M/F). It analyzes birth data, environmental factors like climate change, and potential links to autism spectrum disorder and RhD blood type.
Area of Science:
- Reproductive biology
- Human demography
- Environmental science
Background:
- This series revisits theories on the sex ratio at birth (M/F), updating a 2015 review.
- Examines classical theories and foundational research in M/F studies.
- Presents an analysis of 88,875,750 live births to quantify M/F.
Discussion:
- Investigates the impact of environmental factors, including earthquakes and climate change, on M/F.
- Explores potential correlations between autism spectrum disorder and M/F.
- Tests the hypothesis of a male-skewed sex ratio in mothers with RhD-positive heterozygosity.
Key Insights:
- Quantifies the sex ratio at birth using a large dataset of live births.
- Identifies environmental and biological factors potentially influencing M/F.
- Proposes theoretical explanations for observed variations in M/F.
Outlook:
- Provides a systematic review of factors affecting M/F.
- Encourages further research and discussion on the complex topic of sex ratio determination.
- Aims to stimulate thought and provide insights into the sex ratio at birth.
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