Latin American consensus on uncomplicated recurrent urinary tract infection-2018

Area of Science:

• Urology
• Infectious Diseases
• Women's Health

Background:

• Recurrent urinary tract infections (UTIs) impact 20-30% of adult women.
• A lack of regional consensus for UTI management necessitates expert guidelines.
• Addressing recurrent UTIs can improve quality of life and reduce antibiotic overuse.

Framework:

• Antibiotics are the primary treatment for symptomatic UTIs, considering local resistance.
• Immunoactive therapy (OM-89) and local estrogen (postmenopausal) are recommended for prophylaxis.
• Behavior modification and D-mannose are lower-grade recommendations.

Implementation:

• Antimicrobial prophylaxis is reserved for cases where non-antimicrobial measures fail.
• Prophylaxis selection depends on sexual activity frequency and pathogen resistance.
• Limited recommendations for probiotics, cranberries, and hyaluronic acid warrant patient discussion.

Implications:

• Establishes the first Latin American consensus on recurrent UTI management.
• Guides clinical practice for healthcare providers in the region.
• Promotes evidence-based strategies for preventing and treating recurrent UTIs.