Related Concept Videos

Simultaneous Electroencephalography and Magnetoencephalography to Identify Seizure-Prone Brain Regions04:40

Simultaneous Electroencephalography and Magnetoencephalography to Identify Seizure-Prone Brain Regions

Source: Papadelis, C., et al., Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy. J. Vis. Exp. (2016). This video demonstrates the method of using electroencephalography (EEG) and magnetoencephalography (MEG) recordings to identify interictal epileptiform discharges (IEDs) and high-frequency oscillations (HFOs) to locate seizure-prone regions in the...
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Impact of Direct Current Stimulation on Evoked Epileptic Seizures in Mouse Brain Slices03:09

Impact of Direct Current Stimulation on Evoked Epileptic Seizures in Mouse Brain Slices

The video demonstrates a study for assessing the impact of direct current stimulation (DCS) on epileptic seizures in mouse brain slices. The brain slices containing the connected medial thalamus (MT) and anterior cingulate cortex (ACC) regions are placed in a multielectrode array (MEA). Electrical stimuli to the MT and seizure-inducing drugs are applied to induce epileptic seizures in the ACC. DCS is then applied to assess its impact on evoked...
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Monitoring the Brain Cortex with a Multi-Electrode Array in Response to Seizure-Inducing Agents04:18

Monitoring the Brain Cortex with a Multi-Electrode Array in Response to Seizure-Inducing Agents

In this video, the effects of transcranial direct-current stimulation (tDCS) on brain slices containing the anterior cingulate cortex (ACC) and thalamus regions are investigated, using a multi-electrode array (MEA) to measure electric signals. By delivering electric pulses and infusing seizure-inducing drugs, the study investigates the ACC response to...
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Monitoring Seizure-Induced Neural Electrical Activity in Brain Slices Using Microelectrode Arrays05:15

Monitoring Seizure-Induced Neural Electrical Activity in Brain Slices Using Microelectrode Arrays

This protocol involves using a microelectrode array (MEA) to record electrical activity in a brain slice exposed to a seizure-inducing drug. The procedure includes positioning the brain slice in an MEA recording chamber, applying electrical stimulation to induce artificial seizures, and analyzing the resulting...
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Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins09:07

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Electroconvulsive seizure (ECS) is an experimental animal model of electroconvulsive therapy for severe depression. ECS globally stimulates activity in the hippocampus, leading to synaptogenesis and synaptic plasticity. Here, we describe methods for ECS induction in rats and for subcellular fractionation of their hippocampi to examine seizure-induced changes in synaptic...
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Direct-current Stimulation and Multi-electrode Array Recording of Seizure-like Activity in Mice Brain Slice Preparation09:39

Direct-current Stimulation and Multi-electrode Array Recording of Seizure-like Activity in Mice Brain Slice Preparation

Studies have shown that cathodal transcranial direct-current stimulation can produce suppressive effects on drug-resistant seizures. In this study, an in vitro experimental setup was devised in which the direct-current stimulation and multielectrode array recording of seizure-like activity were evaluated in mice brain slice preparation. The direct-current stimulation parameters were...
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