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Updated: Jan 19, 2026

Fluorescence Lifetime Imaging of Molecular Rotors in Living Cells
Published on: February 9, 2012
Rigidochromic conjugated polymers carrying main-chain molecular rotors
Pieter van der Scheer1, Quintin van Zuijlen1, Joris Sprakel1
1Physical Chemistry and Soft Matter, Wageningen University & Research, Stippeneng 4, 6708WE, Wageningen, The Netherlands. joris.sprakel@wur.nl.
Abstract:
We design and prepare rigidochromic conjugated polymers that carry molecular rotors in the main chain. We show how a suitable design maintains the mechanosensitivity of the rotors upon incorporation into an extended π-conjugated system. Construction of donor-acceptor polymers enables their use as ratiometric probes for polymer micromechanics, which we evidence through micromechanical imaging of a phase-separated polymer blend.
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