Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

6.8K
The isolated-check visual evoked potential (icVEP) method is implemented here to assess the magnocellular ON pathway that is initially damaged in glaucoma. The study shows standard operative procedures using icVEP to obtain reliable results. It is proved to serve as a useful objective diagnosing technology for the early detection of...
6.8K
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

3.4K
Here, we describe the use of spectral-domain optical coherence tomography (SD-OCT) to visualize retinal and ocular structures in vivo in models of retinal degeneration, glaucoma, diabetic retinopathy, and...
3.4K
In Vivo Imaging of the Mouse Retina Using Optical Coherence Tomography04:08

In Vivo Imaging of the Mouse Retina Using Optical Coherence Tomography

719
Source: Jagodzinska, J., et. al.,  Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo. J. Vis. Exp. (2017)  In this video, we demonstrate the use of spectral-domain optical coherence tomography (SD-OCT) to image retinal layers and assess structural changes in a genetically modified mouse model with optic...
719
Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

11.9K
Photoacoustic ophthalmology (PAOM), an optical-absorption-based imaging modality, provides the complementary evaluation of the retina to the currently available ophthalmic imaging technologies. We report the using of PAOM integrated with spectral-domain optical coherence tomography (SD-OCT) for simultaneous multimodal retinal imaging in...
11.9K
Alignment of Visible-Light Optical Coherence Tomography Fibergrams with Confocal Images of the Same Mouse Retina07:02

Alignment of Visible-Light Optical Coherence Tomography Fibergrams with Confocal Images of the Same Mouse Retina

2.1K
The present protocol outlines the steps for aligning in vivo visible-light optical coherence tomography fibergraphy (vis-OCTF) images with ex vivo confocal images of the same mouse retina for the purpose of verifying the observed retinal ganglion cell axon bundle morphology in the in vivo images.
2.1K
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

9.3K
Optical coherence tomography (OCT) is a high resolution imaging technique that allows analysis of tissue specific optical properties providing the means for tissue differentiation. We developed needle based OCT, providing real-time imaging combined with on-the-spot tumor differentiation. This publication describes a method for percutaneous, needle based OCT of renal...
9.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel surgical correction technique of involutional entropion by combined triangular tarsectomy, orbicularis muscle tightening and inferior retractor plication.

European journal of ophthalmology·2023
Same author

Unilateral surgery for pediatric sensory exotropia: clinical characteristics and surgical results.

BMC ophthalmology·2022
Same author

Exenterate or Not: A Simple Proposed Management Algorithm for Mucormycosis During the Era of COVID-19 in a Tertiary Eye Care Center in Egypt.

Clinical ophthalmology (Auckland, N.Z.)·2022
Same author

Concurrent and Post COVID-19 Ophthalmological Implications.

Clinical ophthalmology (Auckland, N.Z.)·2021
Same author

A Proposed Diagnostic Algorithm for Fungal Orbital Infections after 20 Years of Experience in a Tertiary Eye Care Center- Egypt.

Ocular immunology and inflammation·2021
Same author

Incidence and Risk Factors for Retinopathy of Prematurity (ROP) in Biggest Neonatal Intensive Care Unit in Itay Elbaroud City, Behera Province, Egypt.

Clinical ophthalmology (Auckland, N.Z.)·2021

Related Experiment Video

Updated: Jan 19, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.8K

Pattern electroretinogram changes in patients with primary open-angle glaucoma in correlation with visual field and

Asmaa M Elgohary1, Hazem A Elbedewy1, Hisham A Saad1

  • 1Department of Ophthalmology, Faculty of Medicine, Tanta University, Tanta, Egypt.

European Journal of Ophthalmology
|September 10, 2019
PubMed
Summary

Pattern electroretinogram (PERG) changes correlate with visual field and retinal nerve fiber layer thickness in primary open-angle glaucoma. PERG, combined with OCT, offers an objective method for assessing glaucoma-related functional loss.

Keywords:
Pattern electroretinogramoptical coherence tomographyretinal nerve fiber layervisual field

More Related Videos

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

3.4K
Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

11.9K

Related Experiment Videos

Last Updated: Jan 19, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.8K
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

3.4K
Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

11.9K

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Medical Imaging

Background:

  • Glaucoma is a leading cause of irreversible blindness.
  • Primary open-angle glaucoma (POAG) is the most common type.
  • Accurate assessment of functional deficit is crucial for glaucoma management.

Purpose of the Study:

  • To investigate pattern electroretinogram (PERG) changes in POAG patients.
  • To correlate PERG findings with visual field (VF) and optical coherence tomography (OCT) measurements.
  • To evaluate PERG's clinical utility in objectively assessing functional loss in glaucoma.

Main Methods:

  • Study included 81 eyes: 50 POAG patients, 16 glaucoma suspects, 15 controls.
  • Standard automated perimetry (SAP) for VF testing.
  • Heidelberg OCT for peripapillary retinal nerve fiber layer (RNFL) thickness.
  • CSO RetiMax for PERG according to ISCEV guidelines.

Main Results:

  • Significant differences in VF mean deviation, RNFL thickness, and PERG parameters across groups (normal, suspect, POAG).
  • Positive correlation between VF mean deviation and RNFL thickness, P50 amplitude, and P50-N95 amplitude.
  • Negative correlation between RNFL thickness and N95 amplitude; positive correlation with P50-N95 amplitude in POAG patients.

Conclusions:

  • RNFL thickness shows significant negative correlation with PERG N95 amplitude and positive correlation with P50-N95 amplitude.
  • PERG, when used with OCT, can objectively evaluate functional loss in glaucoma.