Related Experiment Video
Updated: Jan 19, 2026
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Day-to-day reliability, agreement and discriminative validity of measuring walking-related performance fatigability
Fanny Van Geel1, Renee Veldkamp1, Deborah Severijns2
1REVAL Rehabilitation Research Center, BIOMED, Faculty of Rehabilitation Sciences, Hasselt University, Diepenbeek, Belgium.
Background:
Day-to-day reliability and cut-off values to detect abnormal walking fatigability (WF) remain to be investigated in persons with multiple sclerosis (pwMS).
Methods:
In all, 49 pwMS (mean Expanded Disability Status Scale (EDSS) ± standard deviation (SD): 3.3 ± 1.9) and 28 matched healthy controls (HC) performed the six-minute walking test (6MWT) on two different days to determine day-to-day reliability (intraclass correlation coefficient (ICC)) and limits of agreement (LOA) for five different equations of WF.
Objective:
To examine day-to-day reliability, agreement and discriminative validity for measuring WF.
Results And Conclusion:
WF expressed as the ratio between the first and sixth minute had the best day-to-day reliability (ICC's range of 0.76-0.95 and 0.60-0.86, respectively) in both pwMS and HC, while LOA were 15% and 7%, respectively. Ecological validity and clinical importance should be further investigated.
Related Concept Videos
11:35The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
01:29Reliability and Validity
07:21Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
09:41Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
08:11Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis
08:18A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis (MS)