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Immunofluorescent Staining of Neuronal Populations in the Embryonic Murine Gastrointestinal Tract
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Sarcina Organisms in the Upper Gastrointestinal Tract: A Report of 3 Cases With Varying Presentations

Robert Propst1, Laura Denham1, Jeremy K Deisch1

  • 1Department of Pathology, Loma Linda University Medical Center and School of Medicine, Loma Linda, CA, USA.

International Journal of Surgical Pathology
|September 10, 2019
PubMed

Insights

Sarcina bacteria, rarely found in the upper GI tract, can cause delayed gastric emptying. Early detection via biopsy and treatment are crucial to prevent severe complications like gastric perforation.

Area of Science:

  • Microbiology
  • Gastroenterology

Background:

  • Sarcina species are anaerobic, gram-positive cocci.
  • They are infrequently identified in the upper gastrointestinal (GI) tract.
  • Sarcina infections are associated with delayed gastric emptying.

Observation:

  • This report details three cases of Sarcina infection.
  • Clinical presentations varied among the patients.
  • One case represents the first documented instance of Sarcina in a patient with eosinophilic esophagitis.

Findings:

  • Sarcina bacteria are often detected only through histopathologic examination of upper GI biopsies.
  • The exact pathogenesis of Sarcina remains incompletely understood.

Implications:

  • Increased awareness of Sarcina is important for clinicians.
  • Prompt diagnosis and treatment in symptomatic individuals can avert serious outcomes.
  • Potential severe complications include emphysematous gastritis and gastric perforation.
Keywords:
Sarcinadelayed gastric emptyingeosinophilic esophagitisgastrointestinal tractpediatric

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