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Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier
Published on: February 8, 2017
Polymeric nanoparticles as carrier for targeted and controlled delivery of anticancer agents
Vahid Taghipour-Sabzevar1, Tahere Sharifi1, Mehrdad Moosazadeh Moghaddam2
1Biomedical Engineering Division, Chemical Engineering Faculty, Tarbiat Modares University, Tehran, Iran.
Abstract:
In recent decades, many novel methods by using nanoparticles (NPs) have been investigated for diagnosis, drug delivery and treatment of cancer. Accordingly, the potential of NPs as carriers is very significant for the delivery of anticancer drugs, because cancer treatment with NPs has led to the improvement of some of the drug delivery limitations such as low blood circulation time and bioavailability, lack of water solubility, drug adverse effect. In addition, the NPs protect drugs against enzymatic degradation and can lead to the targeted and/or controlled release of the drug. The present review focuses on the potential of NPs that can help the targeted and/or controlled delivery of anticancer agents for cancer therapy.
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