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Haplotype analysis in a 16-year-old boy with vancomycin-induced DRESS syndrome
Nazlı Ercan1, Sait Yeşillik2, Fevzi Demirel2
1Department of Pediatric Health and Diseases, Pediatric Immunology and Allergy, University of Health Sciences, Gulhane Training and Research Hospital, Etlik Ankara, Turkey.
Abstract:
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare but life-threatening multisystem adverse reaction to a medication, with vancomycin being one of the most common cause reported. We present the HLA analysis of a pediatric patient who developed DRESS related to vancomycin and compared the results with the available literature. With further data, the use of pretreatment HLA analysis to prevent vancomycin related DRESS may be a valuable option in the near future.
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