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Updated: Jan 19, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Facio-Oculo-Palatal Myoclonus Complicated by a Recurrent Brainstem Stroke.
Yuvadee Pitakpatapee1, Prachaya Srivanitchapoom1
1Division of Neurology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, TH.
Facio-oculo-palatal myoclonus (FOPM) developed in a stroke patient, indicating brainstem lesions. This condition serves as a key diagnostic sign for cerebrovascular diseases affecting the Guillain-Mollaret triangle.
Area of Science:
- Neurology
- Neuroscience
- Clinical Medicine
Background:
- A 54-year-old Thai male experienced multiple ischemic and hemorrhagic strokes.
- One month post-brainstem stroke, the patient developed facio-oculo-palatal myoclonus (FOPM).
Observation:
- Patient presented with involuntary, jerky, horizontal ocular oscillations.
- Asymmetrical palatal and perioral myoclonus were also observed.
- Symptoms were consistent with the diagnostic criteria for FOPM.
Findings:
- Facio-oculo-palatal myoclonus (FOPM) is a rare condition.
- FOPM can serve as a clinical indicator of lesions in the brainstem, particularly the Guillain-Mollaret triangle.
- Cerebrovascular diseases are the most frequent cause of FOPM.
Implications:
- FOPM may aid in the early diagnosis of brainstem lesions.
- Understanding the link between stroke and FOPM can improve patient outcomes.
- Further research into the pathophysiology of FOPM post-stroke is warranted.
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