Existence of pulses for a reaction-diffusion system of blood coagulation in flow

Nicolas Ratto1, Martine Marion1, Vitaly Volpert2,3,4,5

  • 1Institut Camille Jordan, UMR 5585 CNRS, Ecole Centrale de Lyon, 69134 Ecully, France.

Related Concept Videos

Diffuse Correlation Spectroscopy to Assess Cerebral Blood Flow in a Mouse Model02:31

Diffuse Correlation Spectroscopy to Assess Cerebral Blood Flow in a Mouse Model

In this video, we demonstrate the diffuse correlation spectroscopy technique to measure cerebral blood flow in a mouse model of mild traumatic brain...
717
Diffuse Correlation Spectroscopy to Measure Cerebral Blood Flow in a Human Subject05:09

Diffuse Correlation Spectroscopy to Measure Cerebral Blood Flow in a Human Subject

Source: Menezes Forti, R. et al. Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies. J. Vis. Exp. (2020)This video demonstrates the use of Diffuse Correlation Spectroscopy (DCS) to measure cerebral blood flow in humans. It outlines the steps for preparing the system, calibrating the probe, positioning it on the participant’s forehead, acquiring scattered light data, and analyzing intensity fluctuations to interpret blood flow dynamics in the...
453
Multispectral Diffuse Reflectance Imaging of Rat Cerebral Blood Flow and Tissue Structure02:16

Multispectral Diffuse Reflectance Imaging of Rat Cerebral Blood Flow and Tissue Structure

Source: Nishidate, I., et al. Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging. J. Vis. Exp. (2017)This video demonstrates the use of multispectral diffuse reflectance imaging to analyze cerebral blood flow, oxygen levels, and tissue structure changes in an anesthetized rat, providing insights into brain hemodynamics and morphology under varying...
407
Helical Organization of Blood Coagulation Factor VIII on Lipid Nanotubes12:24

Helical Organization of Blood Coagulation Factor VIII on Lipid Nanotubes

We present a combination of Cryo-electron microscopy, lipid nanotechnology, and structure analysis applied to resolve the membrane-bound structure of two highly homologous FVIII forms: human and porcine. The methodology developed in our laboratory to helically organize the two functional recombinant FVIII forms on negatively charged lipid nanotubes (LNT) is...
12.7K
Physiological Pharmacokinetic Models: Blood Flow-Limited Versus Diffusion-Limited Models00:57

Physiological Pharmacokinetic Models: Blood Flow-Limited Versus Diffusion-Limited Models

Physiological pharmacokinetic models, often called flow-limited or perfusion models, typically assume a swift drug distribution between tissue and venous blood, creating a rapid drug equilibrium. This premise is based on the idea that drug diffusion is extremely fast, and the cell membrane presents no barrier to drug permeation. In this scenario, where no drug binding occurs, the drug concentration in the tissue equals that of the venous blood leaving the tissue. This greatly simplifies the...
335
Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow09:41

Hemocompatibility Testing of Blood-Contacting Implants in a Flow Loop Model Mimicking Human Blood Flow

This protocol describes a comprehensive hemocompatibility evaluation of blood-contacting devices using laser-cut neurovascular implants. A flow loop model with fresh, heparinized human blood is applied to mimic blood flow. After perfusion, various hematologic markers are analyzed and compared to the values gained directly after blood collection for hemocompatibility evaluation of the tested...
10.0K