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Updated: Jan 19, 2026

Author Spotlight: Utilization of Decellularized Spleen Matrix for Bioartificial Livers
Published on: February 9, 2024
Sclerosing angiomatoid nodular transformation of the spleen
Jiaying Liao1, Aya Musbahi1, Kaushik Dasgupta2
1General Surgery, North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, UK.
Abstract:
The authors described a case of sclerosing angiomatoid nodular transformation of the spleen (SANT) in a 50-year-old woman presented with persistent neutrophilia and unintentional weight loss. An incidental splenic mass was initially found on abdominal ultrasound. It was found to be progressive in size and with high likelihood of central necrosis on further CT of abdomen and pelvis. The patient subsequently underwent an uneventful laparoscopic splenectomy. The splenic specimens were sent for laboratory analysis and the histopathological findings were highly suggestive of SANT. The patient then had routine surgical follow-ups and was eventually discharged with no further clinical concern.
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