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Updated: Jan 19, 2026
Characterization of Small Bowel Neuroendocrine Tumor Spheroids Using Immunofluorescence
Published on: April 28, 2025
Neuroendocrine tumor associate with inflammatory bowel disease: two cases report
Jeancarlos J Trujillo-Díaz1, Francisco Blanco-Antona1, Javier Ortiz de Solórzano-Aurusa1
1Servicio de Cirugía General y del Aparato Digestivo, Hospital Clínico Universitario de Valladolid, Valladolid, España.
Introduction:
Patients with inflammatory bowel disease (IBD) have a higher risk of developing gastrointestinal tumors, the adenocarcinoma is the most frequently associated, and neuroendocrine tumor (NET) the most rare.
Clinical Cases:
We present two patients, one with Crohn's disease and the other with ulcerative colitis, who present nonspecific symptoms, and after resection of an intestinal lesion, a gastrointestinal NET (GINET) is diagnosed.
Discussion And Conclusion:
The GINET have an insidious clinic and these can be confused with those of the IBD. There could be an association between both pathologies; an important role of the chronic intestinal inflammatory process is suggested. The best treatment for GINET is the resection.
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Characterization of Small Bowel Neuroendocrine Tumor Spheroids Using Immunofluorescence
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