Related Experiment Video
Updated: Jan 19, 2026
Quantitative Susceptibility Mapping of a Human Brain Using Ex-Vivo Magnetic Resonance Imaging
Published on: May 30, 2025
Quantitative susceptibility mapping (QSM) evaluation of infantile neuroaxonal dystrophy
Takuya Fujiwara1, Yoshiyuki Watanabe1, Hisashi Tanaka1
1Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, Suita, Japan.
Abstract:
We present the first case of twins with infantile neuroaxonal dystrophy evaluating brain iron deposition using quantitative susceptibility mapping (QSM). A 6-year-old boy who was normal at birth had psychomotor regression and hypotonia from 2-years-old. Brain MRI showed low intensity areas in globus pallidus (GP) and substantia nigra (SN) on T 2* weighted imaging. QSM values of GP and SN were 0.19 and 0.29 ppm, respectively. His twin brother showed almost the same imaging findings. Follow-up MRI revealed increase of QSM value in GP and SN.
Related Concept Videos
Quantitative Susceptibility Mapping of a Human Brain Using Ex-Vivo Magnetic Resonance Imaging
07:54Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence
Quantitative Strain Mapping of an Abdominal Aortic Aneurysm
1Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana
2Mechanical Engineering & Materials Science, Washington University in St. Louis, St Louis, Missouri
The mechanical behavior of soft tissues, such as blood vessels, skin, tendons, and other organs, are strongly influenced by their composition of elastin and collagen, which provide elasticity and strength. The fiber...
05:54A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy
07:22Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
12:35Simultaneous Mapping and Quantitation of Ribonucleotides in Human Mitochondrial DNA

