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Updated: Jan 19, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Isolated caecal necrosis-a case study.

Nathan Howard Ho Leung Chan¹, Hameed Rafiee¹, Ian L P Beales²

¹Department of Radiology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK.

BJR Case Reports

|September 11, 2019

Summary

This summary is machine-generated.

Isolated caecal necrosis, a rare form of ischemic colitis, was diagnosed in a patient with right iliac fossa pain. CT angiography revealed superior mesenteric artery stenosis, confirmed by colonoscopy and pathology.

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Necrosis

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Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation

Comprehensive Analysis of Procoagulant Platelets Exhibiting Features of Necrosis, Apoptosis and Platelet Activation

Published on: May 23, 2025

Area of Science:

Gastroenterology
Radiology
Vascular Surgery

Background:

Ischemic colitis can present with varied clinical and imaging findings, sometimes mimicking other abdominal pathologies.
Right iliac fossa pain is a common symptom that can be associated with diverse conditions.
Superior mesenteric artery (SMA) stenosis is a significant risk factor for mesenteric ischemia.

Purpose of the Study:

To report a rare case of isolated caecal necrosis secondary to superior mesenteric artery stenosis.
To highlight the diagnostic challenges and imaging findings of focal bowel ischemia.
To emphasize the importance of recognizing risk factors for ischemic colitis.

Main Methods:

A patient presenting with right iliac fossa pain was evaluated.
Computed tomography (CT) angiography was performed to assess vascular supply.
Colonoscopy and histopathological analysis were conducted for definitive diagnosis.

Main Results:

CT angiography revealed isolated caecal necrosis with concurrent superior mesenteric artery (SMA) stenosis.
Colonoscopic findings and subsequent histopathology confirmed the diagnosis of ischemic colitis.
The findings underscore the potential for SMA stenosis to cause focal colonic ischemia.

Conclusions:

Isolated caecal necrosis is an uncommon manifestation of ischemic colitis.
Awareness of risk factors and characteristic CT findings (bowel wall thickening, pneumatosis) is crucial for accurate diagnosis.
Multimodality imaging and diagnostic confirmation are essential for managing mesenteric ischemia.