Primary Diffuse Large B-cell Lymphoma of the Sigmoid Colon

Area of Science:

• Gastroenterology
• Oncology
• Hematology

Background:

• Primary gastrointestinal lymphoma is the most common extranodal lymphoma, with the stomach being the most frequent site.
• Primary colorectal lymphoma is rare, accounting for approximately 3% of all gastrointestinal lymphomas and 0.3% of large intestinal malignancies.
• B-cell non-Hodgkin lymphoma, particularly diffuse large B-cell lymphoma (DLBCL), is the predominant subtype.

Observation:

• An 85-year-old male presented with symptoms indicative of bowel obstruction.
• Diagnostic evaluation revealed primary non-Hodgkin lymphoma of the colon.

Findings:

• The patient was diagnosed with diffuse large B-cell lymphoma (DLBCL) of the colon.
• This case underscores the presentation of colorectal lymphoma mimicking bowel obstruction.

Implications:

• Early recognition of colorectal lymphoma is crucial for timely diagnosis and treatment.
• This case contributes to the understanding of rare gastrointestinal malignancies.
• Further research into the specific characteristics and management of primary colorectal DLBCL is warranted.