[Modifiable and non-modifiable risk factors for urolithiasis]

Knowledge of the risk factors for urolithiasis is the key for sufficient metaphylaxis and reduction of recurrence events. Modifiable risk factors include diet, drink quantity, occupation, environmental factors, number of pregnancies and the intestinal microbiome. The treatment of associated diseases, such as the various manifestations of metabolic syndrome can reduce the risk for urolithiasis and recurrences. Knowledge of non-modifiable risk factors, such as gender, ethnicity, positive family history as well as specific genetic defects and polymorphisms of the calcium and phosphate balance enables personalized counselling and follow-up of affected patients.