Progress in Conductive Polyaniline-Based Nanocomposites for Biomedical Applications: A Review

Area of Science:

• Materials Science
• Biomedical Engineering
• Polymer Chemistry

Background:

• Inherently conducting polymers (ICPs) possess unique electro-optic properties due to conjugated chains.
• Polyaniline (PANI) is a notable ICP with excellent electrical conductivity and biocompatibility.
• PANI's limitations in processability and degradability can be addressed through nanocomposite formation.

Purpose of the Study:

• To review the biological activities and biomedical applications of conductive PANI-based nanocomposites.
• To highlight the latest advancements in PANI nanocomposites for various medical fields.
• To provide a foundation for future research in this area.

Main Methods:

• Literature review of existing research on PANI-based nanocomposites.
• Analysis of studies focusing on biological activities and specific biomedical applications.
• Synthesis and characterization of PANI blends and nanocomposites were discussed.

Main Results:

• PANI-based nanocomposites demonstrate significant potential in antimicrobial therapy, drug delivery, biosensors, nerve regeneration, and tissue engineering.
• The incorporation of PANI into nanocomposites improves its processability and functionality for biomedical uses.
• Nanostructured morphology of PANI contributes to its enhanced performance in biological systems.

Conclusions:

• Conductive PANI-based nanocomposites offer versatile solutions for diverse biomedical challenges.
• Further research into PANI nanocomposites can unlock new therapeutic and diagnostic possibilities.
• Optimizing PANI nanocomposite design is crucial for advancing their clinical translation.