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Updated: Jan 19, 2026
Wireless and Noninvasive Blood Pressure Measurement System
Published on: April 30, 2023
Accuracy of fully automated oscillometric central aortic blood pressure measurement techniques
Michael Gotzmann1, Maximilian Hogeweg2, Felix S Seibert3
1University Hospital St Josef Hospital Bochum, Cardiology, Ruhr University Bochum.
Insights
Two automated devices accurately measure central aortic blood pressure (cBP), a key cardiovascular risk predictor. These findings support the clinical use of noninvasive oscillometric monitors for cBP assessment.
Area of Science:
- Cardiology
- Biomedical Engineering
- Clinical Measurement
Background:
- Central aortic blood pressure (cBP) is a crucial indicator of cardiovascular risk.
- Current limitations in automated measurement devices hinder widespread clinical adoption of cBP.
- This study evaluates novel automated oscillometric devices for cBP assessment.
Purpose of the Study:
- To compare the accuracy of two novel automated oscillometric devices against invasive cBP measurements.
- To assess the feasibility of implementing noninvasive cBP measurement in routine clinical practice.
Main Methods:
- A cross-sectional study involving 502 patients undergoing elective coronary angiography.
- Simultaneous noninvasive cBP assessment using SphygmoCor XCEL and Mobil-O-Graph NG devices.
- Comparison of noninvasive readings with invasively measured cBP.
Main Results:
- Both devices demonstrated high correlation with invasive cBP measurements (SphygmoCor: systolic R 0.864, diastolic R 0.772; Mobil-O-Graph: systolic R 0.763, diastolic R 0.618).
- SphygmoCor XCEL showed higher correlations and lower biases compared to Mobil-O-Graph NG.
- Successful noninvasive cBP measurement was achieved in 99% of patients with SphygmoCor XCEL and 88% with Mobil-O-Graph NG.
Conclusions:
- Automated oscillometric devices can assess cBP with acceptable accuracy.
- SphygmoCor XCEL and Mobil-O-Graph NG show potential for facilitating cBP implementation in clinical practice.
- This study represents the largest validation to date for noninvasive cBP measurement techniques.
Background:
Central aortic blood pressure (cBP) is a valuable predictor of cardiovascular risk. The lack of fully automated measurement devices impeded an implementation in daily clinical practice so far. The present study compares two novel automated oscillometric devices with invasively measured cBP.
Methods:
From March 2017 to March 2018, we enrolled consecutive patients undergoing elective coronary angiography to this cross-sectional study. Noninvasive assessment of cBP was performed by the SphygmoCor XCEL device and the Mobil-O-Graph NG device simultaneously to invasive measurement.
Results:
Our study included 502 patients (228 women, 274 men) with a mean age of 67.9 ± 11.6 years. The noninvasive measurement of cBP was successful in 498 patients (99%) with SphygmoCor XCEL device and in 441 patients (88%) with Mobil-O-Graph NG device (P = 0.451). Measurements of both devices revealed a high correlation to invasively measured systolic (SphygmoCor R 0.864, P < 0.001; Mobil-O-Graph R 0.763, P < 0.001) and diastolic (SphygmoCor R 0.772, P < 0.001; Mobil-O-Graph R 0.618, P < 0.001) cBP. Both devices slightly underestimated systolic and overestimated diastolic central blood pressure: biases were -5.0 ± 7.7/0.5 ± 6.2 mmHg with SphygmoCor XCEL and -6.0 ± 10.4/3.6 ± 8.3 mmHg with Mobil-O-Graph NG device. Correlations (R) were higher and biases were lower with the SphygmoCor device (P < 0.001 each).
Conclusion:
The present study is the largest validation study of noninvasive cBP measurement techniques so far and shows that two current automated oscillometric monitors are able to assess cBP with acceptable accuracy. Automated oscillometric devices may facilitate the implementation of cBP in daily clinical practice.
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