Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration10:14

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

4.2K
Laboratory assays can leverage prognostic value from the longitudinal optical coherence tomography (OCT)-based multimodal imaging of age-related macular degeneration (AMD). Human donor eyes with and without AMD are imaged using OCT, color, near-infrared reflectance scanning laser ophthalmoscopy, and autofluorescence at two excitation wavelengths prior to tissue...
4.2K
Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures07:05

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

2.9K
We present a method, which utilizes a generalizable area-based image analysis approach to identify cell counts. Analysis of different cell populations exploited the significant cell height and structure differences between distinct cell types within an adaptive...
2.9K
Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy (FSM)19:16

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy (FSM)

16.5K
Selection, microinjection, and imaging of fluorescently-labeled F-actin via fluorescent speckle microscopy (FSM).
16.5K
How to Build a Laser Speckle Contrast Imaging (LSCI) System to Monitor Blood Flow05:24

How to Build a Laser Speckle Contrast Imaging (LSCI) System to Monitor Blood Flow

24.5K
This video demonstrates how to build a Laser Speckle Contrast Imaging (LSCI) system that can easily be used to monitor blood...
24.5K
Incorporating Target Protein Structure Flexibility and Dynamics in Computational Drug Discovery Using Ensemble-Based Docking Analysis08:49

Incorporating Target Protein Structure Flexibility and Dynamics in Computational Drug Discovery Using Ensemble-Based Docking Analysis

1.1K
Computational methods hold promises for expediting drug discovery, yet they frequently overlook the dynamic nature of protein structures. Here, we discuss ensemble-based docking analysis to indirectly incorporate protein flexibility, potentially improving the accuracy and reliability of drug discovery...
1.1K
Assessing Intracardiac Vortices with High Frame-Rate Echocardiography-Derived Blood Speckle Imaging in Newborns07:13

Assessing Intracardiac Vortices with High Frame-Rate Echocardiography-Derived Blood Speckle Imaging in Newborns

1.9K
The present protocol uses echocardiography-derived blood speckle imaging technology to visualize intracardiac hemodynamics in newborns. The clinical utility of this technology is explored, the rotational body of fluid within the left ventricle (known as a vortex) is accessed, and its significance in understanding diastology is...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The relationship between perfectionism, neuroticism, and exercise addiction risk: a latent profile analysis and the mediating role of social physique anxiety.

Frontiers in psychology·2026
Same author

Circulating Antinephrin Antibodies in Adult Chinese Patients With IgAN and Nephrotic-Range Proteinuria.

Kidney international reports·2026
Same author

Structures of the endophytic microbiota during heart rot development in <i>Abies georgei</i> var. <i>smithii</i>.

Microbiology spectrum·2026
Same author

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
Same author

Time poverty and access-based consumption: Convenience gains and risk blindness.

British journal of psychology (London, England : 1953)·2026
Same author

High-specificity kilobase-level multiplex PCR enabled by graphene oxide-dendrimer-encapsulated gold nanoparticles.

Journal of materials chemistry. B·2026

Related Experiment Video

Updated: Jan 19, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.2K

BM3D-based total variation algorithm for speckle removal with structure-preserving in OCT images.

Shengjian Huang, Chen Tang, Min Xu

    Applied Optics
    |September 11, 2019
    PubMed
    Summary

    We developed a new BM3D-TV method for optical coherence tomography (OCT) image denoising. This method effectively reduces speckle noise while preserving crucial image structures, significantly improving overall image quality.

    More Related Videos

    Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
    07:05

    Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

    Published on: February 15, 2022

    2.9K
    Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM
    19:16

    Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM

    Published on: August 5, 2009

    16.5K

    Related Experiment Videos

    Last Updated: Jan 19, 2026

    Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
    10:14

    Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

    Published on: May 26, 2023

    4.2K
    Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
    07:05

    Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

    Published on: February 15, 2022

    2.9K
    Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM
    19:16

    Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM

    Published on: August 5, 2009

    16.5K

    Area of Science:

    • Biomedical Imaging
    • Image Processing
    • Computational Science

    Background:

    • Optical coherence tomography (OCT) is crucial for visualizing biological tissues, but suffers from speckle noise.
    • Existing denoising methods like Total Variation (TV) and Block Matching 3D (BM3D) have limitations in preserving image structures.
    • Effective speckle reduction in OCT is vital for accurate diagnosis and analysis.

    Purpose of the Study:

    • To introduce a novel denoising method, BM3D-TV, combining Total Variation and Block Matching 3D for OCT images.
    • To develop a fast numerical algorithm for the proposed BM3D-TV method using split Bregman iteration.
    • To optimize the balance between noise reduction and structural preservation in OCT images.

    Main Methods:

    • Proposed the BM3D-TV method incorporating total variation, data fidelity, and block matching terms.
    • Developed a fast numerical algorithm based on split Bregman iteration for efficient computation.
    • Optimized weighting between data fidelity and block matching terms for enhanced performance.

    Main Results:

    • The BM3D-TV method demonstrated superior speckle noise reduction in OCT images compared to TV and BM3D.
    • Quantitative evaluations showed significant improvements in signal-to-noise ratio and contrast-to-noise ratio.
    • The method effectively protected essential structural information within the OCT images.

    Conclusions:

    • The BM3D-TV method offers a significant advancement in OCT image denoising.
    • It provides an optimal balance between speckle reduction and structural preservation.
    • This technique enhances overall OCT image quality, aiding in better interpretation and analysis.