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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

In this study, the authors report for the first time a novel 3D-Immersive & Interactive Neuronavigation (3D-IIN) through the impact of a spontaneous migraine headache attack in the μ-opioid system of a patient's brain in...
18.7K
Minimally Invasive Surgical Decompression of Occipital Nerves04:06

Minimally Invasive Surgical Decompression of Occipital Nerves

The manuscript presents a minimally invasive nerve and muscle-sparing surgical protocol to decompress occipital nerves aiming to improve occipital...
3.2K
Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro16:13

Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro

Migraine and its transformation to chronic migraine are immense healthcare burdens in need of improved treatment options. We seek to define how neural immune signaling modulates the susceptibility to migraine, modeled in vitro using spreading depression in hippocampal slice cultures, as a means to develop novel therapeutic...
20.4K
Microvascular Decompression: Salient Surgical Principles and Technical Nuances10:35

Microvascular Decompression: Salient Surgical Principles and Technical Nuances

There are many available options for management of the patient with trigeminal neuralgia. Microvascular decompression, while the most invasive of all options, is also the most effective at achieving long term remission of symptoms. Video instruction on how to maximize efficacy and minimize complications with this procedure is...
47.2K
Investigating Migraine-Like Behavior Using Light Aversion in Mice05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Rodents are not able to report migraine symptoms. Here, we describe a manageable test paradigm (light/dark and open field assays) to measure light aversion, one of the most common and bothersome symptoms in patients with migraines.
4.4K
Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

The most notable symptom of migraine is severe head pain, and it is hypothesized that this is mediated by sensory neurons innervating the meninges. Here, we present a method to locally apply substances to the dura in a minimally invasive manner while using facial hypersensitivity as an output.
9.6K