Related Experiment Video
Updated: Aug 8, 2026
08:12
Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
Amelogenesis imperfecta, dentinogenesis imperfecta and dentin dysplasia revisited: problems in classification
1Department of Oral Sciences, University of Minnesota, Minneapolis 55455.
Journal of Oral Pathology
|November 1, 1988
Summary
This study updates the classification and prevalence of amelogenesis imperfecta using new literature. It also discusses issues with the current classification of inherited dentin defects.
Area of Science:
- Dentistry
- Genetics
- Oral Biology
Background:
- Amelogenesis imperfecta (AI) is a group of inherited disorders affecting tooth enamel formation.
- Current classifications of AI may not fully encompass its diverse clinical and genetic presentations.
- Inherited dentin defects also present classification challenges.
Purpose of the Study:
- To provide an updated classification and prevalence data for amelogenesis imperfecta.
- To critically evaluate the existing classification systems for inherited dentin defects.
- To highlight areas for future research in dental developmental anomalies.
Main Methods:
- Systematic literature review of recent studies on amelogenesis imperfecta.
- Analysis of diagnostic criteria and prevalence data from published research.
- Comparative review of classification systems for AI and inherited dentin defects.
Main Results:
- New data refines the understanding of amelogenesis imperfecta prevalence across different populations.
- Identified limitations and inconsistencies in current AI classification schemes.
- Highlighted significant challenges in classifying various inherited dentin defects.
Conclusions:
- An updated classification framework for amelogenesis imperfecta is proposed.
- Recommendations are made for improving the classification of inherited dentin defects.
- Further research is needed to standardize diagnostic criteria and genetic correlations for these conditions.
Related Concept Videos
01:15Teeth
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
01:21Tooth Anatomy
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
01:24Cellular Adaptation IV: Dysplasia and Metaplasia
DysplasiaDysplasia refers to abnormal changes in the size, shape, and organization of mature cells, characterized by pleomorphism, nuclear abnormalities, and increased mitotic activity. It commonly affects epithelial tissues, including the cervix, gastrointestinal tract, respiratory mucosa, and endometrium. Although it may occur alongside hyperplasia, dysplasia is not a true adaptive response but a preneoplastic change with potential to progress to cancer.When confined above the basement...