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Updated: Jan 19, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.6K

ICD shocks in LVAD patients are not associated with increased subsequent mortality risk

Aswini Kumar1,2, Varun Tandon3, David M O'Sullivan4

  • 1Division of Cardiology, Hartford Hospital, Hartford, CT, USA. Drop2ash@gmail.com.

Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing
|September 12, 2019
PubMed

Insights

Implantable cardioverter-defibrillator (ICD) shocks and ventricular arrhythmias (VAs) do not increase mortality risk in continuous flow left ventricular assist device (CF-LVAD) patients. Pre-existing VAs predict future arrhythmias but do not impact survival outcomes in this population.

Area of Science:

  • Cardiology
  • Medical Devices
  • Heart Failure Management

Background:

  • Implantable cardioverter-defibrillator (ICD) shocks are linked to higher mortality in heart failure patients.
  • The impact of ICD shocks on mortality in continuous flow left ventricular assist device (CF-LVAD) patients remains unclear.

Purpose of the Study:

  • To investigate the association between ICD shocks, ventricular arrhythmias (VAs), and mortality in CF-LVAD patients.
  • To identify predictors of VAs in patients with CF-LVAD support.

Main Methods:

  • Retrospective analysis of prospectively collected data from 157 CF-LVAD patients who received ICD therapy.
  • Evaluation of post-LVAD sustained VAs, appropriate/inappropriate ICD shocks, and mortality.
  • Cox multivariate regression analysis to identify predictors of VAs.

Main Results:

  • 30.6% of patients experienced post-LVAD sustained VAs, with 19.1% receiving appropriate ICD shocks.
  • Neither VAs nor ICD shocks were associated with increased mortality risk.
  • Pre-LVAD VAs were a significant predictor of post-LVAD VAs (OR 3.284, p=0.001).

Conclusions:

  • Ventricular arrhythmias are common in CF-LVAD patients, particularly those with prior VAs.
  • Neither VAs nor ICD shocks demonstrated a significant association with mortality in this patient cohort.
  • VAs frequently cause symptoms, but not mortality, in CF-LVAD recipients.
Abstract

Keywords:
ICD shocksLVADMortalitySymptomsVentricular arrhythmia

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