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Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
Published on: September 27, 2017
Body mass index and serum lipid profile: Association with atopic dermatitis in a paediatric population
Pedro Jesús Agón-Banzo1, Rosalía Sanmartin2, Ana Julia García-Malinis3
1Perpetuo Socorro, San Jorge Hospital, Huesca, Spain.
Insights
Children with atopic dermatitis have a higher prevalence of overweight, obesity, and dyslipidemia compared to healthy children. This study highlights the increased risk of metabolic issues in pediatric atopic dermatitis patients.
Area of Science:
- Pediatric Dermatology
- Metabolic Health
- Clinical Research
Background:
- The relationship between atopic dermatitis, body weight, and serum lipid profiles in children remains underexplored.
- Limited research exists on these associations within pediatric populations.
Purpose of the Study:
- To investigate the association between atopic dermatitis and body weight in children.
- To examine the relationship between atopic dermatitis and serum lipid levels in pediatric patients.
Main Methods:
- A prospective cross-sectional study involving 239 children under 14 years old.
- Data collected included age, gender, weight, height, atopic dermatitis severity, and serum lipid levels (total cholesterol, LDL, HDL, triglycerides).
Main Results:
- Children with atopic dermatitis showed a slightly higher mean body mass index (BMI) than healthy controls.
- Significantly higher BMI was observed in younger (0-2 years) and older (12-14 years) atopic dermatitis patients.
- Severe atopic dermatitis correlated with higher BMI in older children (9-14 years).
- Patients with severe atopic dermatitis had higher mean serum total cholesterol and triglycerides compared to the overall atopic dermatitis group.
Conclusions:
- Children diagnosed with atopic dermatitis exhibit a greater prevalence of overweight, obesity, and dyslipidemia.
- These metabolic abnormalities are more common in pediatric atopic dermatitis patients than in their healthy peers.
Background/Objectives:
The association between atopic dermatitis, body weight and serum lipid levels is not well known, and very few studies have examined this relationship in children.
Methods:
Children (n = 239) under 14 years old participated in this prospective cross-sectional study. The following variables were recorded: age, gender, weight, height, atopic dermatitis severity, serum levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides.
Results:
Mean body mass index was slightly higher in atopic dermatitis patients than healthy controls and significantly higher in atopic dermatitis patients aged 0-2 years (atopic dermatitis, 16.7 ± 4.6; controls, 15.7 ± 1.3; P = 0.04) and 12-14 years (atopic dermatitis, 24.9 ± 5.3; controls, 20.6 ± 3.4; P = 0.03). Among atopic dermatitis patients, body mass index was significantly higher in those with severe atopic dermatitis in the 9-12 (P = 0.03) and 12-14 (P = 0.01) years groups. Mean serum lipid levels were higher in patients with severe atopic dermatitis than in the atopic dermatitis group as a whole. These differences reached statistical significance for total cholesterol (P = 0.04) and triglycerides (P = 0.02).
Conclusion:
The prevalence of overweight, obesity and dyslipidemia is greater in children with atopic dermatitis than in age-matched healthy counterparts.
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