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Updated: Jan 19, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Kirsti Malterud1,2,3, Susanne Reventlow1, Ann Dorrit Guassora1
1The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
This study explores how general practitioners (GPs) reach diagnostic conclusions using Lonergan’s theory of knowing. The theory includes three cognitive structures: experiencing, understanding, and judging. The authors apply this framework to a real-world case study to show how GPs interpret patient presentations and develop diagnostic ideas. The study finds that diagnostic knowing is interpretative and contextualized, involving questions that emerge from the GP’s experience rather than fixed hypotheses. The analysis leads to four diagnostic labels: a corn, constipation, headache, and atrial fibrillation. The study suggests that diagnostic processes involve reflexive actions and that Lonergan’s theory provides a useful framework for analyzing clinical reasoning. The findings may have implications for clinical teaching by offering a structured way to discuss and analyze diagnostic processes in general practice.
Area of Science:
Background:
Accurate diagnosis is essential for guiding healthcare decisions, yet the process of reaching a diagnosis remains complex and often underexplored. While traditional models emphasize pattern recognition or hypothesis testing, these approaches may overlook the interpretative and subjective nature of clinical reasoning. Prior research has shown that diagnostic decisions involve more than just logical deduction—they often rely on experience, intuition, and contextual understanding. However, the specific mechanisms through which general practitioners (GPs) interpret patient presentations remain unclear. This gap motivated the use of a theoretical framework to explore how diagnostic knowing is constructed in real-world clinical settings. The study addresses the need for a more nuanced understanding of diagnostic reasoning that accounts for the interpretive and reflexive dimensions of clinical practice. By applying Lonergan’s theory of knowing, the authors aim to uncover the cognitive structures that underpin diagnostic decisions. This approach allows for a deeper exploration of how GPs navigate uncertainty and ambiguity in everyday consultations. The study contributes to the broader field of medical education by offering a framework for analyzing diagnostic processes beyond conventional models.
Purpose Of The Study:
The purpose of the study is to analyze diagnostic knowing in general practice using Lonergan’s theory of knowing, which includes three cognitive structures: experiencing, understanding, and judging. The authors aim to demonstrate how these structures help GPs interpret patient presentations and arrive at diagnostic conclusions. By applying this framework to a real-world case, the study seeks to highlight the interpretative and contextual nature of diagnostic reasoning. The motivation for this approach stems from the recognition that traditional models of diagnosis may not fully capture the complexity of clinical decision-making. The study also aims to show how diagnostic knowing is not purely deductive but involves a series of interpretive and reflexive actions. The authors want to provide a more transparent and systematic way of analyzing how GPs develop diagnostic ideas. This approach could improve clinical teaching by offering a structured way to discuss and reflect on diagnostic processes. Ultimately, the study aims to expand the understanding of diagnosis in general practice beyond conventional models.
Main Methods:
The study uses Lonergan’s theory of knowing as a conceptual framework to analyze a general practice case. The theory includes three cognitive structures: experiencing, understanding, and judging. The authors apply these structures to a real-world diagnostic scenario to explore how GPs interpret patient presentations. The analysis is based on a single case study, which allows for a detailed examination of diagnostic knowing in context. The researchers focus on how diagnostic ideas emerge from patient interactions and how these ideas are developed and judged. The method emphasizes interpretative and reflexive aspects of clinical reasoning rather than purely deductive processes. The approach allows for a transparent and systematic analysis of diagnostic knowing. The study does not rely on statistical methods or large datasets but instead uses qualitative analysis of a single case to illustrate broader principles. The framework helps map the cognitive processes involved in reaching diagnostic conclusions.
Main Results:
The analysis revealed that diagnostic knowing in general practice is interpretative and contextualized. The case study led to four diagnostic labels: a corn, constipation, headache, and atrial fibrillation. These labels were not necessarily derived from deductive reasoning but emerged from interpretive questions rather than fixed hypotheses. The study showed that diagnostic ideas often come from the GP’s experience and interpretations during the consultation. These ideas are then judged and subjected to reflection, which may involve transitory concerns that are not fully ruled out. The analysis demonstrated how Lonergan’s theory fits well with the complexities of diagnostic knowing in general practice. The findings suggest that diagnostic processes involve a series of interpretive and reflexive actions rather than a linear, hypothesis-driven approach. The study provides a framework for understanding how GPs navigate uncertainty and ambiguity in everyday practice.
Conclusions:
The study concludes that diagnostic knowing in general practice is a complex, interpretative process that involves experiencing, understanding, and judging. Lonergan’s theory of knowing provides a useful framework for analyzing this process in a transparent and systematic way. The authors suggest that an interpretative understanding of diagnosis can complement traditional hypothetico-deductive strategies. This approach allows for a more nuanced understanding of how GPs develop diagnostic ideas. The study also highlights the importance of reflexivity in clinical reasoning, as GPs often question and reflect on their diagnostic assumptions. The findings may have implications for clinical teaching by offering a structured way to discuss and analyze diagnostic processes. The authors propose that this interpretative model can enhance clinical practice by recognizing additional diagnostic modes beyond conventional models. The study emphasizes the need for further exploration of how diagnostic knowing can be systematically analyzed and taught in medical education.
Lonergan’s theory includes three cognitive structures: experiencing, understanding, and judging. These structures help GPs interpret patient presentations and develop diagnostic ideas through interpretive and reflexive actions.
The case study identified four diagnostic labels: a corn, constipation, headache, and atrial fibrillation.
Diagnostic knowing is interpretative because it involves questions emerging from the GP’s experience and interpretations rather than fixed diagnostic hypotheses.
Reflexivity allows GPs to question and reflect on diagnostic ideas, including transitory concerns that may not be fully ruled out.
Lonergan’s theory maps clinical reasoning by identifying how GPs experience, understand, and judge patient presentations to form diagnostic conclusions.
The study suggests that an interpretative model of diagnosis can enhance clinical teaching by offering a structured way to analyze and discuss diagnostic processes.