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Related Experiment Video

Updated: Jan 19, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
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Cognitive-Postural Interference in Multiple Sclerosis.

Ludivine Chamard Witkowski1,2,3, Mathieu Mallet1, Mathieu Bélanger1,2,3

  • 1Vitality Health Network, Dr. Georges-L.-Dumont University Hospital Centre, Moncton, NB, Canada.

Frontiers in Neurology
|September 12, 2019
PubMed
Summary

Cognitive-postural interference (CPI) is common in Multiple Sclerosis (MS) patients, impacting balance and increasing fall risk. Studies show postural interference during dual-tasking, but cognitive performance data is often missing.

Keywords:
balancecognitioncognitive-postural interferencedual-taskmultiple sclerosispostural control

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Area of Science:

  • Neuroscience
  • Rehabilitation Science

Background:

  • Multiple Sclerosis (MS) is a neurodegenerative disease impacting balance and cognition, increasing fall risk.
  • Postural control is cognitively demanding, and the interaction can be assessed using dual-task paradigms.
  • Cognitive-postural interference (CPI) quantifies this interaction, often measured by dual-task cost (DTC).

Approach:

  • A systematic review guided by the Prisma statement was conducted to summarize literature on CPI in MS patients.
  • 14 articles were included, all assessing CPI using DTC in MS participants.
  • Studies utilized various cognitive tasks (Stroop Color-Word Test, Word List Generation, Backward Counting) combined with a double stance postural task.

Key Points:

  • Cognitive-postural interference (CPI) is prevalent in Multiple Sclerosis (MS) patients.
  • Postural interference was observed in most studies during dual-tasking.
  • Cognitive task performance data was frequently unavailable, hindering DTC calculation in 11 studies.
  • Postural task performance did not correlate with Expanded Disability Status Scale (EDSS) levels.

Conclusions:

  • The review confirms the presence of CPI in MS patients, often manifesting as postural interference during dual tasks.
  • Standardized reporting of both cognitive and postural performance in single and dual-task conditions is recommended.
  • Future research should employ specific cognitive tasks like the Stroop Color-Word Test with clear prioritization instructions for dual-task assessments.