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Updated: Jan 19, 2026

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings
Published on: February 7, 2025
Donated human milk use and subsequent feeding pattern in neonatal units
Wesam Alyahya1, Debbie Barnett2, Andrew Cooper2
11Human Nutrition, School of Medicine, Dentistry and Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Donated human milk (DHM) is a safe option when mother's own milk (MOM) is unavailable, primarily for preterm infants. Introducing DHM as the first feed does not impact the later availability of MOM for neonates.
Area of Science:
- Neonatal care
- Human milk research
- Clinical auditing
Background:
- Donated human milk (DHM) serves as a safe alternative to mother's own milk (MOM).
- Clinical indications for DHM and its effect on feeding practices require further clarification.
- This study audits DHM use and its impact on subsequent MOM availability.
Purpose of the Study:
- To audit the utilization of donated human milk (DHM) within a specific clinical setting.
- To investigate the influence of initiating enteral feeding with DHM on the subsequent availability of mother's own milk (MOM).
Main Methods:
- Retrospective audit of DHM recipients at Royal Hospital for Children, Glasgow (2014-2016).
- Data collected from an electronic database, analyzed using descriptive statistics.
- Kruskal Wallis test and ANOVA used to assess the association between first milk feed type and subsequent MOM availability, adjusting for confounders.
Main Results:
- 165 DHM recipients identified; 69% born <32 weeks gestation.
- Preterm infants were the primary recipients; DHM use adhered to guidelines in 87% of cases.
- Initial feed type (DHM, MOM, or both) did not significantly affect subsequent MOM availability in preterm neonates.
Conclusions:
- DHM is predominantly used for preterm neonates per local guidelines.
- The introduction of DHM as the initial enteral feed does not impede the subsequent availability of mother's own milk.
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