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The relationship between body mass index and preeclampsia: A systematic review and meta-analysis
Morteza Motedayen1, Mohammad Rafiei2, Mostafa Rezaei Tavirani3
1Department of Cardiology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Insights
Elevated body mass index (BMI) is significantly linked to an increased risk of preeclampsia, a serious pregnancy complication. This finding suggests BMI could aid in early preeclampsia diagnosis.
Area of Science:
- Obstetrics and Gynecology
- Public Health
- Epidemiology
Background:
- Pregnancy-induced hypertension, particularly preeclampsia, is a major cause of maternal and fetal mortality.
- Preeclampsia presents significant health risks for both mother and fetus.
Purpose of the Study:
- To systematically review and meta-analyze the association between body mass index (BMI) and preeclampsia in Iran.
- To quantify the relationship between BMI and preeclampsia risk within the Iranian population.
Main Methods:
- A systematic review and meta-analysis of studies published between 2000 and 2016 in Iran.
- Data from 16 studies involving 5,946 participants were analyzed using a random-effects model in STATA.
- Searches were conducted in SID, PubMed, and Scopus databases using relevant keywords.
Main Results:
- Mean BMI values were 25.13 kg/m² in healthy individuals, 27.42 kg/m² in mild preeclampsia cases, and 26.33 kg/m² in severe preeclampsia cases.
- A statistically significant relationship was observed between BMI and the risk of developing preeclampsia.
Conclusions:
- Body mass index is significantly associated with the risk of preeclampsia.
- BMI may serve as a potential biomarker for diagnosing preeclampsia.
- Further research can explore BMI's role in preeclampsia prediction and management.
Background:
One of the causes of maternal and fetal mortality and morbidity is pregnancy-induced hypertension, the most common form of which is preeclampsia that causes many complications for mother and fetus.
Objective:
The aim of this systematic review and meta-analysis was to determine the relationship between body mass index (BMI) and preeclampsia in Iran.
Materials And Methods:
Using valid keywords in the SID database, PubMed, Scopus, data obtained from all the articles, which were reviewed in Iran between 2000 and 2016, were combined using the meta-analysis method (random-effects model) and analyzed using STATA version 11.1.
Results:
A total number of 5,946 samples were enrolled in 16 studies with the mean BMI values of 25.13, 27.42, and 26.33 kg /m in the healthy, mild, and severe preeclamptic groups, respectively.
Conclusion:
The results of this study revealed that there is a significant relationship between BMI and the risk of preeclampsia, so it can be said that BMI may be one of the ways to diagnose preeclampsia.
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