Related Experiment Video
Updated: Jan 19, 2026
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Why are we still using opioids for osteoarthritis?
1Department of Internal Medicine, New York University Langone Health, New York City, NY, USA.
Abstract:
Osteoarthritis is a common debilitating condition affecting a substantial portion of the population and is an accepted consequence of ageing and overuse. Whilst surgical interventions are a definitive approach, most cases are managed medically with analgesia. Pharmacological therapies have included acetaminophen, non-steroidal anti-inflammatory drugs and opiates. Although significant controversies exist in the use of opioids for chronic musculoskeletal pain, many leading guidelines continue to recommend its use despite increasing evidence to suggest an increase in addiction, morbidity and mortality. With the opiate crisis growing, we re-examine the role opiates have in this chronic condition and current data, and briefly evaluate alternative therapies.
Related Concept Videos
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Opioid Receptors: Overview
09:26The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse
Opioid Analgesics: Morphine and Other Natural Cogeners
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
07:51Synovial Fluid Analysis to Identify Osteoarthritis

