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Related Concept Videos

Prediction Intervals01:03

Prediction Intervals

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The interval estimate of any variable is known as the prediction interval. It helps decide if a point estimate is dependable.
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y. 
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MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor05:54

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High-intensity MRI guided focused ultrasound is an emerging noninvasive technique to precisely ablate brain tissue. It has been shown to be safe and effective in treating medically-refractory essential tremor. This article describes the protocol for thalamotomy from patient selection to equipment setup to post-treatment follow-up.
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Surface Electromyographic Biofeedback as a Rehabilitation Tool for Patients with Global Brachial Plexus Injury Receiving Bionic Reconstruction09:14

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Optimal functional outcomes after bionic reconstruction in patients with global brachial plexus injury depend on a structured rehabilitation protocol. Surface electromyographic guided training may improve the amplitude, separation and consistency of EMG signals, which - after elective amputation of a functionless hand - control and drive a prosthetic...
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Receiver Operating Characteristic Plot01:15

Receiver Operating Characteristic Plot

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A ROC (Receiver Operating Characteristic) plot is a graphical tool used to assess the performance of a binary classification model by illustrating the trade-off between sensitivity (true positive rate) and specificity (false positive rate). By plotting sensitivity against 1 - specificity across various threshold settings, the ROC curve shows how well the model distinguishes between classes, with a curve closer to the top-left corner indicating a more accurate model. The area under the ROC curve...
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Confidence Intervals01:21

Confidence Intervals

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An unbiased point estimate is often insufficient to predict a population estimate, such as population mean or population proportion. In this scenario, a confidence interval is used. A confidence interval is an estimate similar to a  sample proportion. However, unlike the point estimate which is a single value, the confidence interval  contains a range of values. These values have lower and upper limits, known as confidence limits, and can be designated as L1 and L2, respectively.
A...
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Three-Dimensional Ultrasonic Needle Tip Tracking with a Fiber-Optic Ultrasound Receiver04:33

Three-Dimensional Ultrasonic Needle Tip Tracking with a Fiber-Optic Ultrasound Receiver

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Accurate and efficient visualization of invasive medical devices is extremely important in many ultrasound-guided minimally invasive procedures. Here, a method for localizing the spatial position of a needle tip relative to the ultrasound imaging probe is...
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Related Experiment Video

Updated: Jan 19, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
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Prolonged QT Interval in Patients Receiving Psychotropic Medications.

Rebecca S Swenson1, Kathleen Murphy-Ende2

  • 1Rebecca S. Swenson, FNP-BC, APNP, University of Wisconsin-Madison, WI, USA.

Journal of the American Psychiatric Nurses Association
|September 12, 2019
PubMed
Summary
This summary is machine-generated.

Prolonged QT interval (PQTI) is a cardiac risk associated with psychotropic medications. This guide helps mental health prescribers manage PQTI risks through safe prescribing and polypharmacy awareness.

Keywords:
prolonged QT intervalprolonged QT syndromepsychotropic medications

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Area of Science:

  • Cardiology
  • Psychiatry
  • Pharmacology

Background:

  • Prolonged QT interval (PQTI) is a cardiac condition linked to psychotropic medication use in mental health.
  • Antipsychotics, antidepressants, and mood stabilizers are notable contributors to PQTI.
  • Understanding PQTI is crucial for safe psychotropic prescribing practices.

Purpose of the Study:

  • To equip mental health prescribers with knowledge on PQTI risk factors, pathophysiology, identification, and management.
  • To provide practical interventions for psychiatric mental health nurse practitioners (PMHNPs).

Main Methods:

  • Review of relevant literature and practice guidelines.
  • Summarization of information with a focus on practical interventions for PMHNPs.
  • Development of evidence-based decision-making trees.

Main Results:

  • Polypharmacy is a primary factor in PQTI development and complications.
  • Co-occurring disorders and medications from multiple providers increase PQTI risks.
  • Awareness of drug interactions (anticancer, antiarrhythmic, antibiotics) is vital for PQTI management.

Conclusions:

  • A strong knowledge base guides safe PMHNP practice regarding PQTI.
  • Decision-making trees aid in thorough assessment and safe treatment of patients on psychotropic medications.
  • Evidence-based interventions are essential for managing PQTI in psychiatric care.