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Updated: Jan 19, 2026

Author Spotlight: Modeling Brain Tumors In Vivo Using Electroporation-Based Delivery of Plasmid DNA Representing Patient Mutation Signatures
Published on: June 23, 2023
Experimental Delineation of Mutational Signatures Is an Essential Tool in Cancer Epidemiology and Prevention
Jiri Zavadil1, Steven G Rozen2
1Molecular Mechanisms and Biomarkers Group, Mechanisms of Carcinogenesis Section , International Agency for Research on Cancer/World Health Organization , 150 cours Albert Thomas , 69008 Lyon , France.
Abstract:
Advances in experimental modeling of the mutational signatures of environmental exposures and endogenous mutagenic processes will elucidate the role of mutagenesis in cancer, facilitate carcinogen classification, and enable new molecular cancer epidemiology studies.
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