Depolarization-evoked release of N-acetyl-L-aspartyl-L-glutamate from rat brain synaptosomes

Depolarization by potassium and veratridine stimulated the release of N-acetyl-L-aspartyl-L-glutamate from crude synaptosomes prepared from the rat mesencephalon and diencephalon. The potassium-evoked release of N-acetyl-L-aspartyl-L-glutamate was calcium-dependent and the stimulatory effect of veratridine was prevented by tetrodotoxin.