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[Dietary Supplements and "Lifestyle"].
Deborah Christof1, Maria Andreea Gamulescu1
1Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg.
Klinische Monatsblatter Fur Augenheilkunde
|September 12, 2019
Summary
Dietary supplements, like those studied in the Age-Related Eye Disease Studies (AREDS), may help slow the progression of age-related macular degeneration (AMD). Lifestyle factors also play a role in managing this eye condition.
Area of Science:
- Ophthalmology
- Nutritional Science
- Gerontology
Background:
- Non-exudative age-related macular degeneration (AMD) currently lacks specific therapeutic options, unlike the exudative form.
- Patients often seek dietary supplements for prevention and to slow AMD progression, believing they reduce oxidative stress in the retina.
Purpose of the Study:
- To discuss the rationale behind specific ingredients in Age-Related Eye Disease Studies (AREDS) supplements.
- To critically evaluate the findings of the AREDS trials regarding AMD.
- To explore the role of "lifestyle" in influencing AMD progression.
Main Methods:
- Review of the rationale for AREDS supplement ingredients.
- Critical examination of AREDS trial results.
- Discussion of lifestyle factors in AMD management.
Main Results:
- The Age-Related Eye Disease Studies (AREDS) are the primary large-scale, prospective, randomized, controlled trials evaluating supplements for AMD.
- AREDS findings form the basis for current dietary recommendations for AMD.
- The article critically analyzes the evidence supporting AREDS supplements.
Conclusions:
- AREDS supplements are based on the only robust clinical trials for AMD dietary interventions.
- Understanding the rationale and results of AREDS is crucial for patients and clinicians.
- Lifestyle modifications may offer an additional avenue for influencing AMD progression.